Precigen, Inc. (NASDAQ:PGEN) Q2 2022 Earnings Conference Call August 8, 2022 4:30 PM ET
Company Participants
Steven Harasym – Vice President and Head of Investor Relations
Helen Sabzevari – President and Chief Executive Officer
Harry Thomasian – Chief Financial Officer
Conference Call Participants
Nick Abbott – Wells Fargo Securities, LLC
Jason Butler – JMP Securities, LLC
Jennifer Kim – Cantor Fitzgerald & Co.
Operator
Good day, and welcome to the Precigen Second Quarter and First Half 2022 Financial Results Conference Call. After today’s presentation, there will be an opportunity to ask questions. [Operator Instructions] Please note, this event is being recorded.
I would now like to turn the conference over to Steve Harasym, Vice President of Investor Relations. Please go ahead.
Steven Harasym
Thank you, operator, and thank you for joining us today. With me are Dr. Helen Sabzevari, President and CEO of Precigen and Harry Thomasian, our CFO. Helen will provide an update on the significant progress we have made across our pipeline programs and highlight our anticipated upcoming milestones. After which Harry will review our second quarter and first half 2022 financial results. Following our prepared remarks, we will open the call to Q&A.
Before we begin, please note that during today’s call, we will make various forward-looking statements. Investors are cautioned that such forward-looking statements are based on current expectations and are subject to risks and uncertainties that could cause actual results or outcomes to differ materially from those indicated on forward-looking statements. Please read the safe harbor statement contained in this presentation as well as risk factors contained in Precigen’s most recent SEC filings for a more complete discussion of the risks and uncertainties.
I would now like to turn the call over to Dr. Sabzevari. Helen?
Helen Sabzevari
Thanks, Steve, and thanks to all of you for joining us today. We are all accurately aware of the seismic shifts that are shaping in new biopharma landscape. The rules of the past for biotech success in terms of access to capital, clinical trials, regulatory pathways, manufacturing, pricing and commercializations are changing. Traditional funding methods have become more challenging and supply chain issues have led to bottlenecks in traditional manufacturing approaches. Clinical trials that relied on centralized product manufacturing to supply products to sites were particularly hard hit, therefore creating the need for a new paradigm.
Biotech companies are basically having to reinvent themselves for these new times. My goal today is for you to leave this call with an understanding of Precigen’s efforts over the last several years that we believe have enabled us to thrive in these uncertain times. Not only that, but we are one of the few companies that have advanced multiple first-in-class clinical platforms and clinical programs in a highly efficient and rapid way during the pandemic.
Localizing our manufacturing process has allowed us to eliminate many of the costs and time constraints inherent to the traditional production methods for cell therapies. This enabled us to adapt to the new biotech landscape while also providing a robust foundation for advancing new treatments for patients quickly.
The key to success is a strategically focused business model designed to optimize resources and generate returns for shareholders and most importantly, treatments for many patients in need.
The Precigen strategy consists of three core pillars as shown here: First, focus on markets with ultra high unmet need. Our deep clinical pipeline intentionally prioritizes disease indications that require new approaches to treat underserved or unserved patient populations. Such indications usually offer potential for rapid development through accelerated regulatory approval pathways. The route to commercialization for these specialty indications includes a relatively focused prescriber base that could allow us to commercialize some of these products on our own. Over the last several years, we have carefully prioritized these indications within our pipeline.
Next, we are optimizing our research, development and manufacturing operations. Our approach employs resources such as Cooperative Research and Development Agreements, or CRADA and making early decisions to favor therapies with the higher probability of success. Our platform technologies are designed to address critical limitations in cell and gene therapy to reduce economic barriers to care.
For example, our overnight UltraCAR-T platform could enable cancer centers across the globe to deliver cutting-edge therapy to patients who require rapid treatment. We expect consistent manufacturing across multiple sites is expected to decrease cost and provide access to a larger patient population.
And finally, we are pursuing differentiated therapies at potentially disruptive prices. Platforms that produce truly differentiated products with substantially lower COGS relative to CGT benchmarks could enable a compelling competitive value proposition in terms of us delivering better, faster, cheaper products. We have changed the paradigm in the development and manufacturing chain to realize efficiencies whenever possible. We believe this commitment to continuous improvement would yield cost savings to the health system at large.
Let me now provide an update on our clinical portfolio, which can be seen on the next slide. First, our UltraCAR-T trials. As previously announced, we received Fast Track designation for PRGN-3006 or UltraCAR-T therapy for acute myeloid leukemia, or AML, an indication with a high unmet need. Fast Track designation can help expedite the FDA review process and facilitate product development. Enrollment is ongoing in the Phase Ib expansion arm at Dose Level 3 with lymphodepletion and we plan to incorporate redosing this year as it’s needed.
We are pleased to announce activation at the Mayo Clinic in Minnesota award renowned cancer center as an expansion site for the Phase Ib study of PRGN-3006. Tech transfer was successfully completed and FDA has cleared Mayo Clinic as a manufacturing site. We anticipate dosing the first patient at Mayo Clinic very soon. This is an important milestone for us and for the platform, as the only company to demonstrate proof-of-concept for a streamline tech transfer and a scale out of the decentralized UltraCAR-T manufacturing using the UltraPorator at multiple medical centers. We anticipate activating additional sites over the next several months. Finally, we are excited to provide Phase I data at major scientific conference in Q4 2022.
As announced earlier, we have also completed enrollment in the dose escalation phase of both the intraperitoneal and intravenous arms of PRGN-3005 Phase I trial, our UltraCAR-T for the treatment of advanced ovarian cancer. After dosing the first patient at Dose Level 1 in the IV arm, the FDA cleared moving directly to Dose Level 3. This allowed us to rapidly complete enrollment in the IV arm of the Phase I dose escalation trial and introduced lymphodepletion at the Dose Level 3 of the IV arm, which has now completed dosing.
Patient follow-up is ongoing, and we are looking forward to report the Phase I data in the first half of 2023. The plan to initiate a multicenter expansion in a Phase Ib trial of PRGN-3005 with tech transfer and site activations are underway at multiple centers. In addition, we intend to incorporate redosing in this trial as needed.
Our next UltraCAR-T trial, PRGN-3007, which is being evaluated in the treatment of advanced receptor tyrosine kinase-like orphan receptor 1-positive or ROR1+ hematological and solid tumors uses our next generation UltraCAR-T technology and incorporates intrinsic PD-1 checkpoint inhibition in addition to the three effector gene CAR, membrane-bound IL15 and a kill switch, expressed in the first generation UltraCAR-T technology.
The Phase Ib umbrella trial in ROR1+ hematological tumors, including chronic lymphocytic leukemia CLL, mantle cell leukemia MCL, acute lymphoblastic leukemia ALL and diffuse large B-cell lymphoma DLBCL and solid tumors, including triple negative breast cancer TNBC. Our team has been working diligently on the complex logistics of the first-in-class next generation UltraCAR-T umbrella trial, which would allow for enrollment of up to five different indications across hematological and solid tumors and decentralized manufacturing. I’m pleased to report that we are on track to initiate dosing soon.
Now turning to our AdenoVerse platform, PRGN-2012. Our AdenoVerse Immunotherapy in recurrent respiratory papillomatosis, RRP, which began dosing in April of 2021, completed enrollment in Phase I study, which included both dose escalation and dose expansion in less than nine months. Patient follow-up is ongoing.
Last year, we provided an R&D update on our broader portfolio. This year, we are planning to provide more targeted updates and are excited to have the opportunity to present to you what we expect to be a compelling investigator-led presentation on the Phase I data in Q4. In addition, we have initiated dosing in the Phase II study and have enrolled 11 patients to date. We look forward to providing you with the regulatory updates as they become available, given the high unmet need of this indication.
Finally, for an update on PRGN-2009, our AdenoVerse Immunotherapy in human papillomavirus HPV-associated cancers. Enrollment is now complete for six patients in the Phase I monotherapy and 11 patients in the combination therapy arms in patients with recurrent or metastatic HPV-associated cancers. Patient follow-up is ongoing. And we anticipate an investigator-led Phase I data presentation, both in the mono and combo arm in the first half of 2023.
Enrollment is ongoing in the Phase II monotherapy arm in newly diagnosed oropharyngeal squamous cell carcinoma patients with 17 patients enrolled to date. We believe this program has a broad potential as HPV associated malignancies account for 5% of all cancers. We are evaluating potential opportunities in indications such as cervical, head and neck and anal cancers.
I would like to conclude this section with an update on AG019, our therapeutic candidate for Type 1 diabetes using our ActoBiotics platform. We continue discussions on the design and manufacturing of the Phase III trial with both the EMA and FDA. Given the chronic nature of the disease, it will require significant investment in Phase III trials, which we believe it will be best served through a partnership. Meanwhile, partnership discussions are continuing and we look forward to updating you on developments as they become available.
I will now turn the call over to Harry, who will review the terms of the Trans Ova cell, our cost reduction initiatives, and our second quarter 2022 financial highlights. Harry?
Harry Thomasian
Thank you, Helen. Good afternoon to everyone joining us today. As announced last month, we have entered into a definitive agreement for the sale of our Trans Ova Genetics subsidiary to the URUS group. Under the terms of the transaction, which we expect to close in the third quarter of this year, we will receive $170 million in cash upfront and up to $10 million in total earnouts tied to Trans Ova’s performance in 2022 and 2023.
The proceeds from this sale will provide non-dilutive funds to pay our convertible notes, which we intend to do so when due and will significantly strengthen our balance sheet. The closing of this transaction remains subject to certain conditions, including HSR approval.
The slide on the screen now summarizes our second quarter and first half 2021 financial highlights. As Helen alluded to earlier, we have pursued a variety of cost reduction initiatives. This includes the right sizing of our corporate overhead and prioritizing our portfolio to efficiently maximize our investments to advance programs through the clinic. In addition, as we pay down our convertible notes, we will not have future interest costs.
I’d like to take a few minutes to review our second quarter and first half financial results. Net cash used in operating activities was $25.8 million during the six months ended June 30, 2022 compared to $24.2 million during the six months ended June 30, 2021. This increase in cash used in operations is primarily due to the reduced cash inflows from our Trans Ova and Exemplar businesses, which we believe to be timing difference.
Cash, cash equivalents, short-term and long-term investments totaled $132.8 million as of June 30, 2022. In addition, consistent with my comment on focusing on cost reduction initiatives, selling, general and administrative costs have decreased for both the three and six months ended June 30, 2022 compared to the prior year periods.
Finally, it’s important to note that as a result of the anticipated Trans Ova Genetics sale, the Trans Ova Genetics business is now classified as a discontinued operation with its assets, liabilities and operations in the prior periods reclassified to conform to the current presentation.
In regards to the Trans Ova sale, as I mentioned a moment ago, the proceeds from this sale provide non-dilutive capital that we can use to address our convertible debt. Taking into account our cash on hand including investments, cost reduction initiatives and expectations for the convertible notes, we believe that we have cash runway into the fourth quarter of 2023. We continue to focus rigorously on the support of our clinical priorities.
I will now turn the call back to Helen. Helen?
Helen Sabzevari
Thank you, Harry. Realizing the clinical and commercial potential of our core assets require continued execution of our clinical and corporate strategies and we expect to achieve a number of important milestones in 2022 shown here. On the corporate side, the sale of Trans Ova Genetics is expected to close in the third quarter, allowing us to address our convertible debt. On the clinical side, we expect to increase our decentralized manufacturing footprint across multiple geographically diverse sites, which expands patient access to our UltraCAR-T investigational treatment.
We expect to initiate the Phase I study of PRGN-3007 in patients with ROR1-positive tumors across five different hematological and solid cancers. We also expect to initiate a multicenter expansion of the ongoing Phase I/Ib trial of PRGN-3006 in patients with AML and Phase Ib trial of PRGN-3005 in patients with advanced recurrent platinum-resistant ovarian cancer. The expansion of both trials will incorporate repeat dosing as needed and the PRGN-3005 trial will also incorporate lymphodepletion at Dose Level 3 of the intravenous arm.
We look forward to presenting additional compelling data from the ongoing Phase I and Ib trials of PRGN-3006 at the major medical conference in Q4 and for PRGN-2012, we are looking forward to sharing a compelling data and providing a strategic regulatory updates as they become available.
That concludes our prepared remarks for today and we are now happy to take your questions. Operator?
Question-and-Answer Session
Operator
We will now begin the question-and-answer session. [Operator Instructions] The first question is from Nick Abbott with Wells Fargo. Please go ahead.
Nick Abbott
Good afternoon. Thanks for taking our questions and congratulations on the Trans Ova sale. Must be a relief. The first question is on Exemplar. Is that business something you want to keep or something that you want to sell to further extend the runway? And then I have a follow-up. Thanks.
Helen Sabzevari
Hi, Nick. Thank you for the question. And as we have mentioned in prior question and answers, our subsidiaries such as Trans Ova as well as Exemplar both are strategic subsidiaries and we have been very happy with the way that we have maximized the value of Trans Ova, which as you can see now, it’s really can address our convertible note. Similarly for an Exemplar, of course, this is a strategic assets that we have, and we are currently evaluating also the position of Exemplar and how in the future can be actually maximized its value as well as how we can use it for advancing the health portfolio of Precigen.
Nick Abbott
Okay. Thanks, Helen. So it sounds like you – part of that then is you might want to keep that because it’s a strategic asset for the company’s internal pipeline. Is that a way to…
Helen Sabzevari
The way we look at this subsidiary is not as necessarily. We are looking at these subsidiary to see at what point and from what perspective we have maximized the value and how financially then that can be used to advance the health portfolio. And if the sell would be the outcome, then obviously that’s one of the paths that we have, and as we have used for Trans Ova.
Nick Abbott
Okay. Thanks. And then through your prepared remarks, for the UltraCAR-T that the FDA has cleared Mayo as the site for clinical manufacturer, what does that entail this process of getting FDA approval to manufacturer on site?
Helen Sabzevari
Yes. So actually this is quite exciting because number one, it shows the power of a decentralized manufacturing, as you know, with all the other CAR-T, TCRs. And in general, all the cell therapies, all of the companies are using certified manufacturers on one site usually, which they have to be certified by FDA. What we have done is really unprecedented because no other company has been able to basically manufacture their CAR-Ts on multiple sites and especially in the hospitals overnight. And the process, obviously since this is the first-in-class and differentiated, the FDA had to look at the comparability of the manufacturing between the sites, for instance.
And as you can see that with the tech transfers and engineering runs that was done at the Mayo Clinic, we were able to establish that comparability and we are very excited about not only expanding this decentralized manufacturing and as part of also this sites being reviewed by FDA. But also, having sites such as Mayo Clinic, which is world renowned and they are very excellent – centers of excellence to join. And one other thing that I would like to add, as we have discussed this Mayo Clinic is one of the first, but we have a group of sites that will be joining us in the next months to come across various states in California, New York, Illinois and Arizona, and in metropolitan around Maryland and DC areas and Virginia. So we have a number of the excellent cancer centers that you will be seeing in the very, very near future in upcoming months for our expansion sites. And we are very excited about that because this really solidifies these decentralized manufacturing ideas.
Nick Abbott
Thanks, Helen. And there are any Precigen employees on site?
Helen Sabzevari
No.
Nick Abbott
Manufacture? No.
Helen Sabzevari
No. Absolutely not. And that’s, again, speaking to the way that we started and perceived this manufacturing and implemented the whole purpose was that this will become a differentiation manufacturing that can be done at the hospitals at the cancer centers overnight with the employees of the hospital. And that’s exactly what we have done.
Nick Abbott
Terrific. Thanks, Helen.
Helen Sabzevari
Sure. Thank you, Nick.
Operator
The next question is from Ben Burnett with Stifel. Please go ahead.
Helen Sabzevari
Hi, Ben.
Unidentified Analyst
Hi. This is [indiscernible]. Hi. Thanks for taking our question. We just had one quick one regarding PRGN-2012. I’m just wondering, I know that you guys are planning an update for the Phase I in the fourth quarter. Could you guys give us any additional color or details of what we might see there in terms of patient size or data presented? Thank you.
Helen Sabzevari
Absolutely. So based on what we mentioned, we finished the Phase I and Phase Ib in December of 2021 total of 15 patients and we are really excited. In the next few months, we will have a dedicated presentation by our investigators on that data, and we will show – as mentioned, we feel this is a extremely compelling data for this rare disease, and especially for the first time showing the power of our AdenoVerse platform in this setting. At the same token, our investigators have moved very rapidly to Phase II. As mentioned, they have already enrolled 15 patients in the Phase II since December, and a very, very exciting time for us with this – with AdenoVerse platform and in RRP setting. So in the next few months, we will be communicating the exact date and time, and we are looking forward to show a very comprehensive set of data.
Operator
[Operator Instructions] The next question comes from Jason Butler with JMP. Please go ahead.
Jason Butler
Hi. Thanks for taking the questions and congrats on all the progress. I just had another one on the UltraCAR-T platform and the tech transfer process. Can you just give us a sense of what you’ve learned from this first process with the Mayo Clinic and how essentially process-driven you think that the incorporation of new sites can be in the future, how quickly it could take to get new sites up and running not just for the same program, but for anything under the platform eventually?
Helen Sabzevari
Yes. Thank you, Jason. Excellent question. That’s exactly the purpose because when we set the first sites and obviously throughout the Phase I arms of the trials, we had generated a substantial amount of data on the manufacturing as well as the assays that are involved and basically the requirements. And as now we’ve finalized the doses and basically going to the expansion Phase Ib, it was extremely important to show that this manufacturing is actually can be replicated similarly on number of sites because the biggest issue that the field of cell therapy has in general, and it doesn’t matter if you look at it from the [details] all the way to the conventional CAR-T cells is manufacturing, manufacturing, manufacturing. And the classic manufacturing you really have one set of CROs that they do this, it’s one, five, and that’s why it’s centralized. And they keep repeating the same thing and nothing changes there.
The fact that we can go from one center to another center and we have basically generated SOPs that they can transfer from centers and generate similar databases. This was really changed the paradigm here. And of course, now as first site has come with Mayo and you can see that in the next few months, very rapidly other sites will come on board. And I think this allows the vision that we had for this decentralized manufacturing around U.S. and eventually globally, because as we will show in the next few months, we have centers across United States that they have gone through the engineering runs, tech transfers, and they start dosing the patients, which requires comparability of manufacturing. Otherwise, you cannot do this if you have not shown that. And that is a very, very important and significant part of our manufacturing, which no other company had.
Jason Butler
That’s great. Thanks, Helen. And then on 2012, obviously you’re continuing dialogue with FDA on the regulatory path, but can you give us any updated thoughts just on what you think the right pivotal program looks like for RRP? Thanks.
Helen Sabzevari
Sure. So as you mentioned, we are in discussions with FDA and regulatory path. Of course, this is a rare disease. And we would like to see that our Phase II and in discussions with the FDA, how we can, basically reduce the time to approvals for this patient population, which are underserved and they have no other choice except surgeries. And we have a very, very dynamic dialogue with the FDA that I can tell you very exciting in regard to see how we can basically rapidly bring this asset to the approval and then basically commercialization for the patients that they deserve. So we will be reporting on that in the next few months. And as I mentioned, the first set of the data on the first 15 patients also, we will be reporting on which we are very excited about. And I think that will give a flavor of how important this platform is for the patients.
Jason Butler
Okay, great. And then just last one for me. Is there any benefit to retiring the convertible notes earlier than the maturity date? Or does that not make sense for you guys? Thanks.
Harry Thomasian
We’re still looking into that. We do not plan to formalize a tender offer, but we may negotiate individually with…
Helen Sabzevari
Yes. And of course, the advantages is we can always look at the reduction of what the factors that we can do and get maybe some relief from the interest that we have.
Jason Butler
Okay, great. Thanks again for taking the questions.
Helen Sabzevari
Sure. Thank you very much, Jason.
Operator
The next question is from Arthur He with H.C. Wainwright. Please go ahead.
Unidentified Analyst
Hey. Good afternoon, everyone. Hey, Helen. This is [indiscernible] for Art He. First, congratulations on the progress during the quarter. I have two quick questions. First is regarding the 3005 and 3006 program for the repeat dosing. I just wonder is there any SOP included in the protocols for the repeat dosing or its meaning as the physician discretion?
Helen Sabzevari
No. First of all, we had to get amendments from FDA for the clinical protocols, which we have received for old programs. However, this is at the discretion of the physicians and on investigators, and that’s important to emphasize because unlike some of the off-the-shelf, that there is a requirement for multiple dosing right upfront, like, 300 million every week for three weeks, which brings you to a 1 billion. Obviously our investigators have been following the patients and looking at the patient. We do not have that kind of a requirement. And therefore, this is at the discretion of the investigators to see if a patient might need based on the kinetic of the expansion or persistent or the course of the disease.
And if that is the case, then they have the option to use this. And again, this really speaks to the differentiated path of UltraCAR-T versus off-the-shelf or all the other CAR because this allows you at any time that you go in and if you need to redose or give another dose, then you add, and that’s the advantage that we have, but no other companies at the moment has that advantage.
Unidentified Analyst
Got it. Thanks for that color. And my second one is regarding the 3007 program. Besides the triple negative breast cancer, could you tell us is there any other solid tumor including in the basket cohort and why specifically you focus on the triple negative breast cancer first? Thank you.
Helen Sabzevari
So yes, thank you for asking in regard to 3007 because this is one of the more complex programs because of the umbrella nature of it. And therefore it was necessary to pass-through the IRBs that really looked at both from a hematological side and the solid tumors. And therefore, that’s one of the aspects that once we receive the IND and we are dosing this year, that’s number one. I want to really mention that to our – basically analyst as well as our reviewer, the complexity of these and the sites that they have to do this. Therefore, they have to have a different review process and a more complex review process. That’s number one.
Number two, in regard to the [3005], this can be expanded in other solid tumors like pancreatic, as well as the lung cancers, but currently with the triple negative breast cancer, this is another, I would say unserved area for CAR-Ts. In general, solid tumors are, but we currently have one in ovarian cancer. And as you know, there is very limited treatment for the patients with the triple negative breast cancer. It’s quite aggressive. And we believe that these UltraCAR-T targeting ROR1 has a very high possibility for this patient population that are the response rates are very similar to ovarian cancer, or I might say even worse. And for that reason, we chose this. At the same token, the ROR1 expression is high on other solid tumor such as lung and pancreatic, and definitely that can be also added to the bucket.
Unidentified Analyst
Thank you for taking my question.
Helen Sabzevari
Sure. Thank you very much.
Operator
The next question is from Jennifer Kim with Cantor Fitzgerald. Please go ahead.
Helen Sabzevari
Hi, Jennifer.
Jennifer Kim
Hey, everyone. Congrats on the progress this quarter and thanks for taking my questions. I have two here. I guess my first question is I understand that the repeat dosing is at the discretion of the investigators. So I’m wondering, do you have a timeline in mind on when we might anticipate having data on patients who do receive repeat dosing? And then my second question is broader, with the Trans Ova divestiture, has anything changed in your mind in terms of portfolio prioritization and added flexibility to explore opportunities that you weren’t able necessarily to consider beforehand? Thanks so much.
Helen Sabzevari
Sure. Thank you, Kim. So in regards to the redosing, we obviously expect, especially, I think, one of the areas that will be quite both in hematological as well as solid tumors, that some of our investigators as they are following their current patients, they will be introducing the redosing. And this is one of the things that we have mentioned over time that one of the shortcomings of the cell therapies, other CAR-Ts and TCRs is that you can only manufacture once and give one time. And then that course is over and both because of the complexity of manufacturing, but also from perspective of the price tag that is associated, which, its – in regard to UltraCAR-T, we have a differentiation here. Yes, we do expect that some of the patients will receive redosing and we look forward in the near future as our investigators following these patients, they will be reporting on that.
And this is one of the reason also, especially, as we go to the solid tumors because the follow-ups are extremely important. And so we can obviously talk about the safety, which on both trials, we have had a great safety data. But at the same token, the follow-ups are important and the prematurely, we do not want especially on a solid tumors discussed results. So we look forward in the upcoming months and in the first – the next half of this year and the first half of 2023, that our investigators will be actually presenting a comprehensive set of data on both hematological and ovarian cancer.
In regard to the Trans Ova and how that shapes our portfolio. Well, actually this is very important because having the convertible note being addressed in a non-dilutive form, I think it has been very, very important for the company because now we do not have to take our other resources and our financial resources to devote to the payment of our non-convertible notes.
As Harry mentioned, we have a solid runway well to the fourth quarter of 2023, which has allowed us to basically go through our – some of the clinical timelines that we have for reporting the data. And I think that’s going to be very good. And we basically do not have to take anything from the financial strength that we have, or I should say the money that we have, currently that is dedicated to our clinical trial and be diverting this for our convertible notes. And that’s – obviously it’s a huge, I think, pressure off at this point, especially during this financial times and not diluting our investor base. So we are very happy about that.
We have prioritized portfolio as we have mentioned in our slides and according to the three pillar of a strategy that we have and we mentioned for instance, even in regard to our AG019, which is a very exciting program for a type 1 diabetes, we feel that this has served best with partnership, which the discussions on our partnerships are ongoing and we look forward to report on that in the near future.
Jennifer Kim
All right. Very helpful. Thanks so much and congrats again.
Helen Sabzevari
Thank you very much.
Operator
This concludes our question-and-answer session. At this time, I would like to turn the conference back to Dr. Sabzevari for closing remarks.
Helen Sabzevari
Thank you, and thank you for taking the time to join us for our update call. We look forward to communicating further in the near future, and we will be in touch for announcement of our discussions on PRGN-2012 in the upcoming months. Thank you very much.
Operator
This concludes the conference. Thank you for attending today’s presentation. You may now disconnect.
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